Jaclyn S Pearson Selected Research

Type III Secretion Systems

1/2020	The Salmonella Effector SseK3 Targets Small Rab GTPases.
1/2017	EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation.
1/2017	Distinct Roles of the Antiapoptotic Effectors NleB and NleF from Enteropathogenic Escherichia coli.
1/2016	Identification of a Distinct Substrate-binding Domain in the Bacterial Cysteine Methyltransferase Effectors NleE and OspZ.
12/2015	Substrate recognition by the zinc metalloprotease effector NleC from enteropathogenic Escherichia coli.
11/2014	The type III secretion effector NleF of enteropathogenic Escherichia coli activates NF-κB early during infection.
8/2014	The Inflammatory Response during Enterohemorrhagic Escherichia coli Infection.
9/2013	A type III effector antagonizes death receptor signalling during bacterial gut infection.
6/2013	Characterization of the ospZ promoter in Shigella flexneri and its regulation by VirB and H-NS.
4/2011	A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jaclyn S Pearson Research Topics

Disease

16	Infections 10/2021 - 04/2011
4	Inflammation (Inflammations) 02/2017 - 04/2014
3	Salmonella Infections (Salmonellosis) 01/2020 - 01/2019
3	Bacterial Infections (Bacterial Infection) 10/2017 - 06/2013
1	Noncommunicable Diseases 01/2021
1	Dysbiosis 01/2021
1	Nervous System Diseases (Neurological Disorders) 01/2021
1	Communicable Diseases (Infectious Diseases) 01/2019
1	Necrosis 01/2017

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 10/2021 - 04/2011
10	Type III Secretion SystemsIBA 01/2020 - 04/2011
4	Death Domain ReceptorsIBA 01/2020 - 09/2013
3	Arginine (L-Arginine)FDA Link 01/2021 - 10/2017
3	Interleukin-8 (Interleukin 8)IBA 01/2016 - 04/2011
2	Phosphotransferases (Kinase)IBA 01/2021 - 01/2017
2	GlycopeptidesIBA 01/2019 - 10/2017
2	Cysteine Proteases (Cysteine Protease)IBA 02/2017 - 01/2017
2	Caspase 8 (Caspase-8)IBA 01/2016 - 11/2014
1	HexosesIBA 01/2021
1	Protein Kinases (Protein Kinase)IBA 01/2021
1	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2021
1	Acetates (Acetic Acid Esters)FDA Link 01/2021
1	Butyrates (Butyrate)IBA 01/2021
1	Pharmaceutical PreparationsIBA 01/2021
1	Volatile Fatty AcidsIBA 01/2021
1	Serine-Threonine Kinase 3IBA 01/2020
1	UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferaseIBA 01/2020
1	AcetylglucosamineIBA 01/2020
1	Interleukin-1 (Interleukin 1)IBA 01/2020
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2020
1	CytokinesIBA 01/2020
1	Monomeric GTP-Binding ProteinsIBA 01/2020
1	rab GTP-Binding ProteinsIBA 01/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2019
1	VaccinesIBA 01/2019
1	LipopolysaccharidesIBA 01/2017
1	CaspasesIBA 01/2017
1	Poly I-CIBA 01/2017
1	Amino Acids FDA Link 01/2016
1	Alanine (L-Alanine)FDA Link 01/2016
1	Caspase 9IBA 11/2014
1	Shiga Toxin (Shigella Toxin)IBA 08/2014
1	Immunologic Factors (Immunomodulators)IBA 08/2014
1	Peptide Hydrolases (Proteases)FDA Link 04/2011